Publications
Below are some of our publications for 2024
Onoja, B. A., Oguzie, J. U., George, U. E., Asoh, K. E., Ajayi, P., Omofaye, T. F., Igeleke, I. O., Eromon, P., Harouna, S., Parker, E., Adeniji, A. J., & Happi, C. T. (2024). Whole genome sequencing unravels cryptic circulation of divergent dengue virus lineages in the rainforest region of Nigeria. Emerging microbes & infections, 13(1), 2307511. https://doi.org/10.1080/22221751.2024.2307511
Kotliar, D., Raju, S., Tabrizi, S., Odia, I., Goba, A., Momoh, M., Sandi, J. D., Nair, P., Phelan, E., Tariyal, R., Eromon, P. E., Mehta, S., Robles-Sikisaka, R., Siddle, K. J., Stremlau, M., Jalloh, S., Gire, S. K., Winnicki, S., Chak, B., Schaffner, S. F., … Sabeti, P. C. (2024). Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever. Nature microbiology, 9(3), 751–762. https://doi.org/10.1038/s41564-023-01589-3
Happi, A. N., Ogunsanya, O. A., Ayinla, A. O., Sijuwola, A. E., Saibu, F. M., Akano, K., Nwofoke, C., Elias, O. T., Achonduh-Atijegbe, O., Daodu, R. O., Adedokun, O. A., Adeyemo, A., Ogundana, K. E., Lawal, O. Z., Parker, E., Nosamiefan, I., Okolie, J., Parker, Z. F., McCauley, M. D., Eller, L. A., … Happi, C. T. (2024). Lassa virus in novel hosts: insights into the epidemiology of lassa virus infections in southern Nigeria. Emerging microbes & infections, 13(1), 2294859. https://doi.org/10.1080/22221751.2023.2294859
Ugwu, C. A., Alao, O., John, O. G., Akinnawo, B., Ajayi, I., Odebode, O., Bejide, I., Campbell, A., Campbell, J., Adole, J. A., B Olawoye, I., Akano, K., Okolie, J., Eromon, P., Olaitan, P., Olagunoye, A., Adebayo, I., Adebayo, V., Babalola, E., Abioye, O., … Happi, C. (2024). Immunological insights into COVID-19 in Southern Nigeria. Frontiers in immunology, 15, 1305586. https://doi.org/10.3389/fimmu.2024.1305586
Aniebo I. (2024). Investment in African research and development will boost health and economic growth. Nature medicine, 30(2), 326. https://doi.org/10.1038/s41591-023-02746-1
Publications
Below are some of our publications for 2023
Oguzie, J. U., Petros, B. A., Oluniyi, P. E., Mehta, S. B., Eromon, P. E., Nair, P., Adewale-Fasoro, O., Ifoga, P. D., Odia, I., Pastusiak, A., Gbemisola, O. S., Aiyepada, J. O., Uyigue, E. A., Edamhande, A. P., Blessing, O., Airende, M., Tomkins-Tinch, C., Qu, J., Stenson, L., Schaffner, S. F., … Happi, C. T. (2023). Metagenomic surveillance uncovers diverse and novel viral taxa in febrile patients from Nigeria. Nature communications, 14(1), 4693. https://doi.org/10.1038/s41467-023-40247-4
George, U., George, O., Oguzie, J., Osasona, O., Motayo, B., Kamani, J., Eromon, P., Folarin, O., Happi, A., Komolafe, I., & Happi, C. (2023). Genomic characterization of Alphacoronavirus from Mops condylurus bats in Nigeria. Virus research, 334, 199174. https://doi.org/10.1016/j.virusres.2023.199174
Uwanibe, J. N., Kayode, T. A., Oluniyi, P. E., Akano, K., Olawoye, I. B., Ugwu, C. A., Happi, C. T., & Folarin, O. A. (2023). The prevalence of undiagnosed Salmonella enterica serovar Typhi in healthy school-aged children in Osun State, Nigeria. Pathogens (Basel, Switzerland), 12(4), 594. https://doi.org/10.3390/pathogens12040594
Happi, A. N., Ayinla, A. O., Ogunsanya, O. A., Sijuwola, A. E., Saibu, F. M., Akano, K., George, U. E., Sopeju, A. E., Rabinowitz, P. M., Ojo, K. K., Barrett, L. K., Van Voorhis, W. C., & Happi, C. T. (2023). Detection of SARS-CoV-2 in terrestrial animals in Southern Nigeria: Potential cases of reverse zoonosis. Viruses, 15(5), 1187. https://doi.org/10.3390/v15051187
Olawoye, I. B., Oluniyi, P. E., Oguzie, J. U., Uwanibe, J. N., Kayode, T. A., Olumade, T. J., Ajogbasile, F. V., Parker, E., Eromon, P. E., Abechi, P., Sobajo, T. A., Ugwu, C. A., George, U. E., Ayoade, F., Akano, K., Oyejide, N. E., Nosamiefan, I., Fred-Akintunwa, I., Adedotun-Sulaiman, K., Brimmo, F. B., … Happi, C. T. (2023). Emergence and spread of two SARS-CoV-2 variants of interest in Nigeria. Nature communications, 14(1), 811. https://doi.org/10.1038/s41467-023-36449-5
Publications
Below are some of our publications for 2022
Ugwu, C., Olumade, T., Nwakpakpa, E., Onyia, V., Odeh, E., Duruiheoma, R. O., Ojide, C. K., Eke, M. A., Nwafor, I. E., Chika-Igwenyi, N., Abu, A. M., Azuogu, B., Ajayi, N., Ogah, E., Ayodeji, O., Abejegah, C., Adedosu, N., Oyejide, N., Abah, S., Omidele, A., … Happi, C. (2022). Humoral and cellular immune responses to Lassa fever virus in Lassa fever survivors and their exposed contacts in Southern Nigeria. Scientific reports, 12(1), 22330. https://doi.org/10.1038/s41598-022-26045-w
Tegally, H., San, J. E., Cotten, M., Moir, M., Tegomoh, B., Mboowa, G., Martin, D. P., Baxter, C., Lambisia, A. W., Diallo, A., Amoako, D. G., Diagne, M. M., Sisay, A., Zekri, A. N., Gueye, A. S., Sangare, A. K., Ouedraogo, A. S., Sow, A., Musa, A. O., Sesay, A. K., … Wilkinson, E. (2022). The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance. Science (New York, N.Y.), 378(6615), eabq5358. https://doi.org/10.1126/science.abq5358
George, U., George, O., Oragwa, A., Motayo, B., Kamani, J., Adamu, A., Sowemimo, O., Adeleke, R., Abalaka, S., Sani, N., Oguzie, J., Eromon, P., Folarin, O., Happi, A., Komolafe, I., & Happi, C. (2022). Detection of alpha- and betacoronaviruses in frugivorous and insectivorous bats in Nigeria. Pathogens (Basel, Switzerland), 11(9), 1017. https://doi.org/10.3390/pathogens11091017
Oguzie, J. U., Nwangwu, U. C., Oluniyi, P. E., Olumade, T. J., George, U. E., Kazeem, A., Bankole, B. E., Brimmo, F. O., Asadu, C. C., Chukwuekezie, O. C., Ochu, J. C., Makwe, C. O., Dogunro, F. A., Onwude, C. O., Nwachukwu, W. E., Ezihe, E. K., Okonkwo, G. K., Umazi, N. E., Maikere, J., Agashi, N. O., … Happi, C. T. (2022). Metagenomic sequencing characterizes a wide diversity of viruses in field mosquito samples in Nigeria. Scientific reports, 12(1), 7616. https://doi.org/10.1038/s41598-022-11797-2
Oluniyi, P. E., Ajogbasile, F. V., Zhou, S., Fred-Akintunwa, I., Polyak, C. S., Ake, J. A., Tovanabutra, S., Iroezindu, M., Rolland, M., & Happi, C. T. (2022). HIV-1 drug resistance and genetic diversity in a cohort of people with HIV-1 in Nigeria. AIDS (London, England), 36(1), 137–146. https://doi.org/10.1097/QAD.0000000000003098
Publications
Below are some of our publications for 2021
Oluniyi, P. E., Ajogbasile, F., Oguzie, J., Uwanibe, J., Kayode, A., Happi, A., Ugwu, A., Olumade, T., Ogunsanya, O., Eromon, P. E., Folarin, O., Frost, S. D. W., Heeney, J., & Happi, C. T. (2021). VGEA: An RNA viral assembly toolkit. PeerJ, 9, e12129. https://doi.org/10.7717/peerj.12129
Olawoye, I. B., Uwanibe, J. N., Kunle-Ope, C. N., Davies-Bolorunduro, O. F., Abiodun, T. A., Audu, R. A., Salako, B. L., & Happi, C. T. (2021). Whole genome sequencing of clinical samples reveals extensively drug resistant tuberculosis (XDR TB) strains from the Beijing lineage in Nigeria, West Africa. Scientific reports, 11(1), 17387. https://doi.org/10.1038/s41598-021-96956-7
Ayoade, F., Oguzie, J., Eromon, P., Omotosho, O. E., Ogunbiyi, T., Olumade, T., Akano, K., Folarin, O., & Happi, C. (2021). Molecular surveillance of shiga toxigenic Escherichia coli in selected beef abattoirs in Osun State Nigeria. Scientific reports, 11(1), 13966. https://doi.org/10.1038/s41598-021-93347-w
Ajogbasile, F. V., Kayode, A. T., Oluniyi, P. E., Akano, K. O., Uwanibe, J. N., Adegboyega, B. B., Philip, C., John, O. G., Eromon, P. J., Emechebe, G., Finimo, F., Ogbulafor, N., Jiya, N., Okafor, U., Ambe, J., Wammanda, R. D., Oguche, S., Mokuolu, O. A., Sowunmi, A., Folarin, O. A., … Happi, C. T. (2021). Genetic diversity and population structure of Plasmodium falciparum in Nigeria: insights from microsatellite loci analysis. Malaria journal, 20(1), 236. https://doi.org/10.1186/s12936-021-03734-x
Kayode, A. T., Akano, K., Ajogbasile, F. V., Uwanibe, J. N., Oluniyi, P. E., Bankole, B. E., Eromon, P. J., Sowunmi, A., Folarin, O. A., Volkman, S. K., McInnis, B., Sabeti, P., Wirth, D. F., & Happi, C. T. (2021). Polymorphisms in Plasmodium falciparum chloroquine resistance transporter (Pfcrt) and multidrug-resistant gene 1 (Pfmdr-1) in Nigerian children 10 years post-adoption of artemisinin-based combination treatments. International journal for parasitology, 51(4), 301–310. https://doi.org/10.1016/j.ijpara.2020.10.001
Publications
Below are some of our publications for 2020
Olawoye, I. B., Frost, S. D. W., & Happi, C. T. (2020). The Bacteria Genome Pipeline (BAGEP): An automated, scalable workflow for bacteria genomes with Snakemake. PeerJ, 8, e10121. https://doi.org/10.7717/peerj.10121
Arizti-Sanz, J., Freije, C. A., Stanton, A. C., Petros, B. A., Boehm, C. K., Siddiqui, S., Shaw, B. M., Adams, G., Kosoko-Thoroddsen, T. F., Kemball, M. E., Uwanibe, J. N., Ajogbasile, F. V., Eromon, P. E., Gross, R., Wronka, L., Caviness, K., Hensley, L. E., Bergman, N. H., MacInnis, B. L., Happi, C. T., … Myhrvold, C. (2020). Streamlined inactivation, amplification, and Cas13-based detection of SARS-CoV-2. Nature communications, 11(1), 5921. https://doi.org/10.1038/s41467-020-19097-x
Sakabe, S., Hartnett, J. N., Ngo, N., Goba, A., Momoh, M., Sandi, J. D., Kanneh, L., Cubitt, B., Garcia, S. D., Ware, B. C., Kotliar, D., Robles-Sikisaka, R., Gangavarapu, K., Branco, L. M., Eromon, P., Odia, I., Ogbaini-Emovon, E., Folarin, O., Okogbenin, S., Okokhere, P. O., … Sullivan, B. M. (2020). Identification of common CD8+ T cell epitopes from lassa fever survivors in Nigeria and Sierra Leone. Journal of virology, 94(12), e00153-20. https://doi.org/10.1128/JVI.00153-20
Sullivan, B. M., Sakabe, S., Hartnett, J. N., Ngo, N., Goba, A., Momoh, M., Demby Sandi, J., Kanneh, L., Cubitt, B., Garcia, S. D., Ware, B. C., Kotliar, D., Robles-Sikisaka, R., Gangavarapu, K., Branco, L., Eromon, P., Odia, I., Ogbaini-Emovon, E., Folarin, O., Okogbenin, S., … Oldstone, M. B. A. (2020). High crossreactivity of human T cell responses between Lassa virus lineages. PLoS pathogens, 16(3), e1008352. https://doi.org/10.1371/journal.ppat.1008352
Cross, R. W., Xu, R., Matassov, D., Hamm, S., Latham, T. E., Gerardi, C. S., Nowak, R. M., Geisbert, J. B., Ota-Setlik, A., Agans, K. N., Luckay, A., Witko, S. E., Soukieh, L., Deer, D. J., Mire, C. E., Feldmann, H., Happi, C., Fenton, K. A., Eldridge, J. H., & Geisbert, T. W. (2020). Quadrivalent VesiculoVax vaccine protects nonhuman primates from viral-induced hemorrhagic fever and death. The Journal of clinical investigation, 130(1), 539–551. https://doi.org/10.1172/JCI131958
Ajogbasile, F. V., Oguzie, J. U., Oluniyi, P. E., Eromon, P. E., Uwanibe, J. N., Mehta, S. B., Siddle, K. J., Odia, I., Winnicki, S. M., Akpede, N., Akpede, G., Okogbenin, S., Ogbaini-Emovon, E., MacInnis, B. L., Folarin, O. A., Modjarrad, K., Schaffner, S. F., Tomori, O., Ihekweazu, C., Sabeti, P. C., … Happi, C. T. (2020). Real-time metagenomic analysis of undiagnosed fever cases unveils a yellow fever outbreak in Edo State, Nigeria. Scientific reports, 10(1), 3180. https://doi.org/10.1038/s41598-020-59880-w
Publications
Below are some of our publications for 2019
Ogunbiyi, T. S., Eromon, P., Oluniyi, P., Ayoade, F., Oloche, O., Oguzie, J. U., Folarin, O., Happi, C., & Komolafe, I. (2019). First report of Wolbachia from field populations of Culex mosquitoes in South-Western Nigeria. African Zoology, 54(3), 181-185. https://doi.org/10.1080/15627020.2019.1649092
Akano, K., Fatunmbi, B., Ntadom, G., Ayede, A. I., Aderoyeje, T., Bakre, A., Alebiosu, O. T., Akpoborie, O., Okafor, C., Gbotosho, G. O., Folarin, O. A., Ebenebe, J. C., Ambe, J., Wammanda, R., Jiya, N., Finomo, F., Emechebe, G., Mokuolu, O., Agomo, C., Oguche, S., … Sowunmi, A. (2019). Clinical illness and outcomes in Nigerian children with persistent early-appearing anaemia following initiation of artemisinin-based combination treatments of uncomplicated falciparum malaria. Clinique et évolution de l’anémie persistante d’apparition précoce chez les enfants nigérians, après traitement combiné à base d’artémisinine du paludisme non compliqué à Plasmodium falciparum. Parasite (Paris, France), 26, 56. https://doi.org/10.1051/parasite/2019058
Happi, A. N., Happi, C. T., & Schoepp, R. J. (2019). Lassa fever diagnostics: Past, present, and future. Current opinion in virology, 37, 132–138. https://doi.org/10.1016/j.coviro.2019.08.002
Sowunmi, A., Ntadom, G., Akano, K., Ibironke, F. O., Ayede, A. I., Agomo, C., Folarin, O. A., Gbotosho, G. O., Happi, C., Oguche, S., Okafor, H. U., Meremikwu, M., Agomo, P., Ogala, W., Watila, I., Mokuolu, O., Finomo, F., Ebenebe, J. C., Jiya, N., Ambe, J., … Oduola, A. (2019). Declining responsiveness of childhood Plasmodium falciparum infections to artemisinin-based combination treatments ten years following deployment as first-line antimalarials in Nigeria. Infectious diseases of poverty, 8(1), 69. https://doi.org/10.1186/s40249-019-0577-x
Okogbenin, S., Okoeguale, J., Akpede, G., Colubri, A., Barnes, K. G., Mehta, S., Eifediyi, R., Okogbo, F., Eigbefoh, J., Momoh, M., Rafiu, M., Adomeh, D., Odia, I., Aire, C., Atafo, R., Okonofua, M., Pahlman, M., Becker-Ziaja, B., Asogun, D., Okokhere, P., … Ogbaini-Emovon, E. (2019). Retrospective cohort study of lassa fever in pregnancy, Southern Nigeria. Emerging infectious diseases, 25(8), 1494–1500. https://doi.org/10.3201/eid2508.181299
Ogunro, B. N., Olugasa, B. O., Kayode, A., Ishola, O. O., Kolawole, O. N., Odigie, E. A., & Happi, C. (2019). Detection of antibody and antigen for Lassa virus nucleoprotein in monkeys from Southern Nigeria. Journal of epidemiology and global health, 9(2), 125–127. https://doi.org/10.2991/jegh.k.190421.001
Metsky, H. C., Siddle, K. J., Gladden-Young, A., Qu, J., Yang, D. K., Brehio, P., Goldfarb, A., Piantadosi, A., Wohl, S., Carter, A., Lin, A. E., Barnes, K. G., Tully, D. C., Corleis, B., Hennigan, S., Barbosa-Lima, G., Vieira, Y. R., Paul, L. M., Tan, A. L., Garcia, K. F., … Matranga, C. B. (2019). Capturing sequence diversity in metagenomes with comprehensive and scalable probe design. Nature biotechnology, 37(2), 160–168. https://doi.org/10.1038/s41587-018-0006-x
Publications
Below are some of our publications for 2018
Bankole, B. E., Kayode, A. T., Nosamiefan, I. O., Eromon, P., Baniecki, M. L., Daniels, R. F., Hamilton, E. J., Durfee, K., MacInnis, B., Okafor, H., Sowunmi, A., Volkman, S. K., Sabeti, P., Wirth, D., Happi, C. T., & Folarin, O. A. (2018). Characterization of Plasmodium falciparum structure in Nigeria with malaria SNPs barcode. Malaria journal, 17(1), 472. https://doi.org/10.1186/s12936-018-2623-8
Akano, K., Ntadom, G., Agomo, C., Happi, C. T., Folarin, O. A., Gbotosho, G. O., Mokuolu, O., Finomo, F., Ebenebe, J. C., Jiya, N., Ambe, J., Wammanda, R., Emechebe, G., Basorun, O. K., Wewe, O. A., Amoo, S., Ezeigwe, N., Oguche, S., Fatunmbi, B., & Sowunmi, A. (2018). Parasite reduction ratio one day after initiation of artemisinin-based combination therapies and its relationship with parasite clearance time in acutely malarious children. Infectious diseases of poverty, 7(1), 122. https://doi.org/10.1186/s40249-018-0503-7
Okokhere, P. O., Erameh, C. O., Alikah, F., Akhideno, P. E., Iruolagbe, C. O., Osazuwa, O. O., Bankole, I. A., Adomeh, D. I., Odia, I., Aire, C. O., Oyakhilome, J., Agbukor, J., Atafo, R. O., Asogun, D. A., Happi, C. T., Sabeti, P. C., Günther, S., & Akpede, G. O. (2018). Acute Lassa virus encephalitis with Lassa virus in the cerebrospinal fluid but absent in the blood: A case report with a positive outcome. Case reports in neurology, 10(2), 150–158. https://doi.org/10.1159/000490374
Ebenebe, J. C., Ntadom, G., Ambe, J., Wammanda, R., Jiya, N., Finomo, F., Emechebe, G., Mokuolu, O., Akano, K., Agomo, C., Folarin, O. A., Oguche, S., Useh, F., Oyibo, W., Aderoyeje, T., Abdulkadir, M., Ezeigwe, N. M., Happi, C., Sowunmi, A., & Antimalarial Therapeutic Efficacy Monitoring Group National Malaria Elimination Programme The Federal Ministry Of Health Abuja Nigeria (2018). Efficacy of artemisinin-based combination treatments of uncomplicated falciparum malaria in under-five-year-old Nigerian children ten years following adoption as first-line antimalarials. The American journal of tropical medicine and hygiene, 99(3), 649–664. https://doi.org/10.4269/ajtmh.18-0115
Herrera, B. B., Hamel, D. J., Oshun, P., Akinsola, R., Akanmu, A. S., Chang, C. A., Eromon, P., Folarin, O., Adeyemi, K. T., Happi, C. T., Lu, Y., Ogunsola, F., & Kanki, P. J. (2018). A modified anthrax toxin-based enzyme-linked immunospot assay reveals robust T cell responses in symptomatic and asymptomatic Ebola virus exposed individuals. PLoS neglected tropical diseases, 12(5), e0006530. https://doi.org/10.1371/journal.pntd.0006530
Boisen, M. L., Hartnett, J. N., Shaffer, J. G., Goba, A., Momoh, M., Sandi, J. D., Fullah, M., Nelson, D. K. S., Bush, D. J., Rowland, M. M., Heinrich, M. L., Koval, A. P., Cross, R. W., Barnes, K. G., Lachenauer, A. E., Lin, A. E., Nekoui, M., Kotliar, D., Winnicki, S. M., Siddle, K. J., … Garry, R. F. (2018). Field validation of recombinant antigen immunoassays for diagnosis of Lassa fever. Scientific reports, 8(1), 5939. https://doi.org/10.1038/s41598-018-24246-w
Yinka-Ogunleye, A., Aruna, O., Ogoina, D., Aworabhi, N., Eteng, W., Badaru, S., Mohammed, A., Agenyi, J., Etebu, E. N., Numbere, T. W., Ndoreraho, A., Nkunzimana, E., Disu, Y., Dalhat, M., Nguku, P., Mohammed, A., Saleh, M., McCollum, A., Wilkins, K., Faye, O., … Ihekweazu, C. (2018). Reemergence of human monkeypox in Nigeria, 2017. Emerging infectious diseases, 24(6), 1149–1151. https://doi.org/10.3201/eid2406.180017
Okokhere, P., Colubri, A., Azubike, C., Iruolagbe, C., Osazuwa, O., Tabrizi, S., Chin, E., Asad, S., Ediale, E., Rafiu, M., Adomeh, D., Odia, I., Atafo, R., Aire, C., Okogbenin, S., Pahlman, M., Becker-Ziaja, B., Asogun, D., Fradet, T., Fry, B., … Sabeti, P. C. (2018). Clinical and laboratory predictors of Lassa fever outcome in a dedicated treatment facility in Nigeria: a retrospective, observational cohort study. The Lancet. Infectious diseases, 18(6), 684–695. https://doi.org/10.1016/S1473-3099(18)30121-X
Publications
Below are some of our publications for 2017
Sowunmi, A., Fatunmbi, B., Akano, K., Wewe, O. A., Agomo, C., Finomo, F., Ebenebe, J., Jiya, N., Ambe, J., Wammanda, R., Ntadom, G., Mokuolu, O., Emechebe, G., Ezeigwe, N., Ayede, A. I., Adewoye, E. O., Gbotosho, G. O., Folarin, O. A., Happi, C. T., Oguche, S., … Useh, F. (2017). Factors contributing to anaemia after uncomplicated falciparum malaria in under five year-old Nigerian children ten years following adoption of artemisinin-based combination therapies as first-line antimalarials. BMC infectious diseases, 17(1), 781. https://doi.org/10.1186/s12879-017-2876-9
Akhuemokhan, O. C., Ewah-Odiase, R. O., Akpede, N., Ehimuan, J., Adomeh, D. I., Odia, I., Olomu, S. C., Pahlmann, M., Becker-Ziaja, B., Happi, C. T., Asogun, D. A., Okogbenin, S. A., Okokhere, P. O., Dawodu, O. S., Omoike, I. U., Sabeti, P. C., Günther, S., & Akpede, G. O. (2017). Prevalence of Lassa Virus Disease (LVD) in Nigerian children with fever or fever and convulsions in an endemic area. PLoS neglected tropical diseases, 11(7), e0005711. https://doi.org/10.1371/journal.pntd.0005711
Sowunmi, A., Akano, K., Ntadom, G., Ayede, A., Oguche, S., Agomo, C., Okafor, H., Watila, I., Meremikwu, M., Ogala, W., Agomo, P., Adowoye, E., Fatunmbi, B., Aderoyeje, T., Happi, C., Gbotosho, G., & Folarin, O. (2017). Anaemia following artemisinin-based combination treatments of uncomplicated Plasmodium falciparum malaria in children: Temporal patterns of haematocrit and the use of uncomplicated hyperparasitaemia as a model for evaluating late-appearing anaemia. Chemotherapy, 62(4), 231–238. https://doi.org/10.1159/000449366
Dudas, G., Carvalho, L. M., Bedford, T., Tatem, A. J., Baele, G., Faria, N. R., Park, D. J., Ladner, J. T., Arias, A., Asogun, D., Bielejec, F., Caddy, S. L., Cotten, M., D’Ambrozio, J., Dellicour, S., Di Caro, A., Diclaro, J. W., Duraffour, S., Elmore, M. J., Fakoli, L. S., … Rambaut, A. (2017). Virus genomes reveal factors that spread and sustained the Ebola epidemic. Nature, 544(7650), 309–315. https://doi.org/10.1038/nature22040
Sowunmi, A., Akano, K., Ayede, A. I., Adewoye, E. O., Ntadom, G., Fatunmbi, B., Gbotosho, G. O., Folarin, O. A., & Happi, C. T. (2017). Early rising asexual parasitaemia in Nigerian children following a first dose of artemisinin-based combination treatments of falciparum malaria. BMC infectious diseases, 17(1), 110. https://doi.org/10.1186/s12879-016-2173-z
Sowunmi, A., Akano, K., Ntadom, G., Ayede, A. I., Ibironke, F. O., Aderoyeje, T., Adewoye, E. O., Fatunmbi, B., Oguche, S., Okafor, H. U., Watila, I., Meremikwu, M., Agomo, P., Ogala, W., Agomo, C., Folarin, O. A., Gbotosho, G. O., & Happi, C. T. (2017). Therapeutic efficacy and effects of artemisinin-based combination treatments on uncomplicated Plasmodium falciparum malaria -associated anaemia in Nigerian children during seven years of adoption as first-line treatments. Infectious diseases of poverty, 6(1), 36. https://doi.org/10.1186/s40249-016-0217-7
Publications
Below are some of our publications for 2016
Salu, O. B., James, A. B., Oke, B. O., Orenolu, M. R., Anyanwu, R. A., Abdullah, M. A., Happi, C., Idris, J., Abdus-Salam, I. A., Nasidi, A. S., Ogunsola, F. T., Tomori, O., & Omilabu, S. A. (2016). Biosafety level-2 laboratory diagnosis of Zaire Ebola virus disease imported from Liberia to Nigeria. African journal of laboratory medicine, 5(1), 468. https://doi.org/10.4102/ajlm.v5i1.468
Adenmosun, O. O., Happi, C., Ogunmodede, O. S., Adesokan, Y., & Opeyemi, O. S. (2016). Preventing Ebola resurgence from zoonotic routes: A random assessment of Bat populations in Osun State, Nigeria. Journal of prevention & infection control, 2(2). https://doi.org/10.21767/2471-9668.100024
Goba, A., Khan, S. H., Fonnie, M., Fullah, M., Moigboi, A., Kovoma, A., Sinnah, V., Yoko, N., Rogers, H., Safai, S., Momoh, M., Koroma, V., Kamara, F. K., Konowu, E., Yillah, M., French, I., Mustapha, I., Kanneh, F., Foday, M., McCarthy, H., … Viral Hemorrhagic Fever Consortium (2016). An outbreak of Ebola Virus Disease in the lassa fever zone. The Journal of infectious diseases, 214(suppl 3), S110–S121. https://doi.org/10.1093/infdis/jiw239
Folarin, O. A., Ehichioya, D., Schaffner, S. F., Winnicki, S. M., Wohl, S., Eromon, P., West, K. L., Gladden-Young, A., Oyejide, N. E., Matranga, C. B., Deme, A. B., James, A., Tomkins-Tinch, C., Onyewurunwa, K., Ladner, J. T., Palacios, G., Nosamiefan, I., Andersen, K. G., Omilabu, S., Park, D. J., … Happi, C. T. (2016). Ebola virus epidemiology and evolution in Nigeria. The Journal of infectious diseases, 214(suppl 3), S102–S109. https://doi.org/10.1093/infdis/jiw190
Yozwiak, N. L., Happi, C. T., Grant, D. S., Schieffelin, J. S., Garry, R. F., Sabeti, P. C., & Andersen, K. G. (2016). Roots, not parachutes: Research collaborations combat outbreaks. Cell, 166(1), 5–8. https://doi.org/10.1016/j.cell.2016.06.029
Robinson, J. E., Hastie, K. M., Cross, R. W., Yenni, R. E., Elliott, D. H., Rouelle, J. A., Kannadka, C. B., Smira, A. A., Garry, C. E., Bradley, B. T., Yu, H., Shaffer, J. G., Boisen, M. L., Hartnett, J. N., Zandonatti, M. A., Rowland, M. M., Heinrich, M. L., Martínez-Sobrido, L., Cheng, B., de la Torre, J. C., … Garry, R. F. (2016). Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits. Nature communications, 7, 11544. https://doi.org/10.1038/ncomms11544
Poznik, G. D., Xue, Y., Mendez, F. L., Willems, T. F., Massaia, A., Wilson Sayres, M. A., Ayub, Q., McCarthy, S. A., Narechania, A., Kashin, S., Chen, Y., Banerjee, R., Rodriguez-Flores, J. L., Cerezo, M., Shao, H., Gymrek, M., Malhotra, A., Louzada, S., Desalle, R., Ritchie, G. R., … Tyler-Smith, C. (2016). Punctuated bursts in human male demography inferred from 1,244 worldwide Y-chromosome sequences. Nature genetics, 48(6), 593–599. https://doi.org/10.1038/ng.3559
Osterholm, M., Moore, K., Ostrowsky, J., Kimball-Baker, K., Farrar, J., & Wellcome Trust-CIDRAP Ebola Vaccine Team B (2016). The Ebola Vaccine Team B: A model for promoting the rapid development of medical countermeasures for emerging infectious disease threats. The Lancet. Infectious diseases, 16(1), e1–e9. https://doi.org/10.1016/S1473-3099(15)00416-8
Publications
Below are some of our publications for 2015
Sudmant, P. H., Rausch, T., Gardner, E. J., Handsaker, R. E., Abyzov, A., Huddleston, J., Zhang, Y., Ye, K., Jun, G., Fritz, M. H., Konkel, M. K., Malhotra, A., Stütz, A. M., Shi, X., Casale, F. P., Chen, J., Hormozdiari, F., Dayama, G., Chen, K., Malig, M., … Korbel, J. O. (2015). An integrated map of structural variation in 2,504 human genomes. Nature, 526(7571), 75–81. https://doi.org/10.1038/nature15394
1000 Genomes Project Consortium, Auton, A., Brooks, L. D., Durbin, R. M., Garrison, E. P., Kang, H. M., Korbel, J. O., Marchini, J. L., McCarthy, S., McVean, G. A., & Abecasis, G. R. (2015). A global reference for human genetic variation. Nature, 526(7571), 68–74. https://doi.org/10.1038/nature15393
Andersen, K. G., Shapiro, B. J., Matranga, C. B., Sealfon, R., Lin, A. E., Moses, L. M., Folarin, O. A., Goba, A., Odia, I., Ehiane, P. E., Momoh, M., England, E. M., Winnicki, S., Branco, L. M., Gire, S. K., Phelan, E., Tariyal, R., Tewhey, R., Omoniwa, O., Fullah, M., … Sabeti, P. C. (2015). Clinical sequencing uncovers origins and evolution of Lassa virus. Cell, 162(4), 738–750. https://doi.org/10.1016/j.cell.2015.07.020
Park, D. J., Dudas, G., Wohl, S., Goba, A., Whitmer, S. L., Andersen, K. G., Sealfon, R. S., Ladner, J. T., Kugelman, J. R., Matranga, C. B., Winnicki, S. M., Qu, J., Gire, S. K., Gladden-Young, A., Jalloh, S., Nosamiefan, D., Yozwiak, N. L., Moses, L. M., Jiang, P. P., Lin, A. E., … Sabeti, P. C. (2015). Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone. Cell, 161(7), 1516–1526. https://doi.org/10.1016/j.cell.2015.06.007
Hartnett, J. N., Boisen, M. L., Oottamasathien, D., Jones, A. B., Millett, M. M., Nelson, D. S., Muncy, I. J., Goba, A., Momoh, M., Fullah, M., Mire, C. E., Geisbert, J. B., Geisbert, T. W., Holton, D. L., Rouelle, J. A., Kannadka, C. B., Reyna, A. A., Moses, L. M., Khan, S. H., … Branco, L. M. (2015). Current and emerging strategies for the diagnosis, prevention and treatment of Lassa fever. Future Virology, 10(5), 559-584. https://doi.org/10.2217/fvl.15.41
Stremlau, M. H., Andersen, K. G., Folarin, O. A., Grove, J. N., Odia, I., Ehiane, P. E., Omoniwa, O., Omoregie, O., Jiang, P. P., Yozwiak, N. L., Matranga, C. B., Yang, X., Gire, S. K., Winnicki, S., Tariyal, R., Schaffner, S. F., Okokhere, P. O., Okogbenin, S., Akpede, G. O., Asogun, D. A., … Happi, C. T. (2015). Discovery of novel rhabdoviruses in the blood of healthy individuals from West Africa. PLoS neglected tropical diseases, 9(3), e0003631. https://doi.org/10.1371/journal.pntd.0003631
Falajiki, Y. F., Akinola, O., Abiodun, O. O., Happi, C. T., Sowunmi, A., & Gbotosho, G. O. (2015). Amodiaquine-Ciprofloxacin: A potential combination therapy against drug resistant malaria. Parasitology, 142(6), 849–854. https://doi.org/10.1017/S0031182015000062
Publications
Below are some of our publications for 2014
Kuhn, J. H., Andersen, K. G., Baize, S., Bào, Y., Bavari, S., Berthet, N., Blinkova, O., Brister, J. R., Clawson, A. N., Fair, J., Gabriel, M., Garry, R. F., Gire, S. K., Goba, A., Gonzalez, J. P., Günther, S., Happi, C. T., Jahrling, P. B., Kapetshi, J., Kobinger, G., … Formenty, P. (2014). Nomenclature- and database-compatible names for the two Ebola virus variants that emerged in Guinea and the Democratic Republic of the Congo in 2014. Viruses, 6(11), 4760–4799. https://doi.org/10.3390/v6114760
Matranga, C. B., Andersen, K. G., Winnicki, S., Busby, M., Gladden, A. D., Tewhey, R., Stremlau, M., Berlin, A., Gire, S. K., England, E., Moses, L. M., Mikkelsen, T. S., Odia, I., Ehiane, P. E., Folarin, O., Goba, A., Kahn, S. H., Grant, D. S., Honko, A., Hensley, L., … Sabeti, P. C. (2014). Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses from clinical and biological samples. Genome biology, 15(11), 519. https://doi.org/10.1186/PREACCEPT-1698056557139770
Schieffelin, J. S., Shaffer, J. G., Goba, A., Gbakie, M., Gire, S. K., Colubri, A., Sealfon, R. S., Kanneh, L., Moigboi, A., Momoh, M., Fullah, M., Moses, L. M., Brown, B. L., Andersen, K. G., Winnicki, S., Schaffner, S. F., Park, D. J., Yozwiak, N. L., Jiang, P. P., Kargbo, D., … WHO Clinical Response Team (2014). Clinical illness and outcomes in patients with Ebola in Sierra Leone. The New England journal of medicine, 371(22), 2092–2100. https://doi.org/10.1056/NEJMoa1411680
Kuhn, J. H., Andersen, K. G., Bào, Y., Bavari, S., Becker, S., Bennett, R. S., Bergman, N. H., Blinkova, O., Bradfute, S., Brister, J. R., Bukreyev, A., Chandran, K., Chepurnov, A. A., Davey, R. A., Dietzgen, R. G., Doggett, N. A., Dolnik, O., Dye, J. M., Enterlein, S., Fenimore, P. W., … Nichol, S. T. (2014). Filovirus RefSeq entries: evaluation and selection of filovirus type variants, type sequences, and names. Viruses, 6(9), 3663–3682. https://doi.org/10.3390/v6093663
Gire, S. K., Goba, A., Andersen, K. G., Sealfon, R. S., Park, D. J., Kanneh, L., Jalloh, S., Momoh, M., Fullah, M., Dudas, G., Wohl, S., Moses, L. M., Yozwiak, N. L., Winnicki, S., Matranga, C. B., Malboeuf, C. M., Qu, J., Gladden, A. D., Schaffner, S. F., Yang, X., … Sabeti, P. C. (2014). Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak. Science (New York, N.Y.), 345(6202), 1369–1372. https://doi.org/10.1126/science.1259657
Badejo, J. A., Abiodun, O. O., Akinola, O., Happi, C. T., Sowunmi, A., & Gbotosho, G. O. (2014). Interaction between rifampicin, amodiaquine and artemether in mice infected with chloroquine resistant Plasmodium berghei. Malaria journal, 13, 299. https://doi.org/10.1186/1475-2875-13-299
Falade, M. O., Akinboye, D. O., Gbotosho, G. O., Ajaiyeoba, E. O., Happi, T. C., Abiodun, O. O., & Oduola, A. M. (2014). In vitro and in vivo antimalarial activity of Ficus thonningii Blume (Moraceae) and Lophira alata Banks (Ochnaceae), identified from the ethnomedicine of the Nigerian Middle Belt. Journal of parasitology research, 2014, 972853. https://doi.org/10.1155/2014/972853
Asogun, D., Tobin, E. A., Gunther, S., Happi, C., & Ikponwosa, O. (2014). Dealing with the unseen: Fear and stigma in lassa fever. International journal of infectious diseases, 21(1), 221. https://doi.org/10.1016/j.ijid.2014.03.881
Tobin, E. A., Asogun, D., Happi, C., Ogbaini, E., & Gunther, S.(2014). Risk factors for Lassa fever in endemic communities of Edo State, Nigeria. International journal of infectious diseases, 21(1), 258–259. https://doi.org/10.1016/j.ijid.2014.03.958
H3Africa Consortium, Rotimi, C., Abayomi, A., Abimiku, A., Adabayeri, V. M., Adebamowo, C., Adebiyi, E., Ademola, A. D., Adeyemo, A., Adu, D., Affolabi, D., Agongo, G., Ajayi, S., Akarolo-Anthony, S., Akinyemi, R., Akpalu, A., Alberts, M., Alonso Betancourt, O., Alzohairy, A. M., Ameni, G., … Zar, H. (2014). Research capacity. Enabling the genomic revolution in Africa. Science (New York, N.Y.), 344(6190), 1346–1348. https://doi.org/10.1126/science.1251546
Shaffer, J. G., Grant, D. S., Schieffelin, J. S., Boisen, M. L., Goba, A., Hartnett, J. N., Levy, D. C., Yenni, R. E., Moses, L. M., Fullah, M., Momoh, M., Fonnie, M., Fonnie, R., Kanneh, L., Koroma, V. J., Kargbo, K., Ottomassathien, D., Muncy, I. J., Jones, A. B., Illick, M. M., … Viral Hemorrhagic Fever Consortium (2014). Lassa fever in post-conflict Sierra Leone. PLoS neglected tropical diseases, 8(3), e2748. https://doi.org/10.1371/journal.pntd.0002748