{"id":1629,"date":"2025-11-17T13:43:49","date_gmt":"2025-11-17T13:43:49","guid":{"rendered":"https:\/\/ighresearch.org\/en\/?page_id=1629"},"modified":"2025-11-17T13:50:41","modified_gmt":"2025-11-17T13:50:41","slug":"human-genomic-centre","status":"publish","type":"page","link":"https:\/\/ighresearch.org\/en\/human-genomic-centre\/","title":{"rendered":"Human Genomic Centre"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"1629\" class=\"elementor elementor-1629\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-aa381ed ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"aa381ed\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-da25a81 ts-bg-color-over-image\" data-id=\"da25a81\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f31445e elementor-widget elementor-widget-heading\" data-id=\"f31445e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A summary of the Human Genomics Centre\n<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-695e386 ts-col-stretched-none ts-bg-color-over-image elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"695e386\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-9491c95 ts-bg-color-over-image\" data-id=\"9491c95\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-50e7bb0 elementor-widget elementor-widget-text-editor\" data-id=\"50e7bb0\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<p><span style=\"font-weight: 400;\">The Human Genome Project is a project that was launched in 2024 at the Institute of Genomics and Global Health (IGH), formerly ACEGID, is a groundbreaking project aiming to lead human genomics sequencing in Africa.\u00a0\u00a0<\/span><\/p><p><b>The key focus areas of the work<\/b><\/p><p><span style=\"font-weight: 400;\">The primary goal of the Human Genomics Center is to become a leading hub for advancing African genetic knowledge.\u00a0 The center\u2019s first initiative is the Human Genome Projec, an initiative to sequence 3 million African genomes.\u00a0 The project will focus both on communicable and non-communicable diseases, including cancer, diabetes, and other lifestyle diseases.\u00a0\u00a0<\/span><\/p><p><span style=\"font-weight: 400;\">Additionally, our human genomic research will be a key element of GenCoE.\u00a0 GenCoE is an emerging initiative, (Genomics Centres of Excellence in Africa) that has already secured a 500k USD seed investment from the Skoll Foundation. The goal is to establish a network <\/span><b>cutting-edge genomics research <\/b><span style=\"font-weight: 400;\">programs and <\/span><b>translating research findings <\/b><span style=\"font-weight: 400;\">for better health on the continent. Africa GenCoE will leverage the extensive <\/span><b>genetic and environmental diversity across Africa <\/b><span style=\"font-weight: 400;\">to drive the generation of new knowledge to <\/span><b>improve the precision and accuracy of healthcare <\/b><span style=\"font-weight: 400;\">for its people and the rest of <\/span><b>the world<\/b><span style=\"font-weight: 400;\">.<\/span><\/p><p><b>Current projects or achievements<\/b><\/p><p><span style=\"font-weight: 400;\">Among its notable achievements, the center made history in November 2024 by successfully sequencing a whole human genome entirely on Nigerian soil for the first time. Illumina has donated the Illumina NovaSeq X Plus sequencer, making it one of the few institutions on the continent capable of performing advanced human genome analysis.<\/span><\/p><p><b>Why this research matters \/ its real-world impact<\/b><\/p><p><span style=\"font-weight: 400;\">\u200bThe Human Genome Project spearheaded by the Institute of Genomics and Global Health (IGH), formerly ACEGID, is a pivotal initiative aimed at addressing the significant underrepresentation of African populations in global genomic research. Despite Africa&#8217;s unparalleled genetic diversity, individuals of African descent constitute only about 1.1% of participants in genome-wide association studies, highlighting a substantial gap in the data used to inform medical research and healthcare solutions worldwide. \u200b<\/span><\/p><p><span style=\"font-weight: 400;\">Sequencing whole human genomes in Nigeria is a first step toward opening new vistas of healthcare opportunities, precision medicine for Africans.<\/span><\/p><p><span style=\"font-weight: 400;\">Africa is recognized as the cradle of modern humans and harbors the highest levels of genetic variation among all continents. This diversity offers invaluable insights into human evolution, disease susceptibility, and the development of effective treatments. By sequencing African genomes, researchers can uncover novel genetic variants that influence health and disease, leading to more accurate diagnostics, personalized therapies, and a better understanding of conditions that disproportionately affect African populations. \u200b<\/span><\/p><p><span style=\"font-weight: 400;\">IGH&#8217;s Human Genome Project is spearheading the work to span this gap.\u00a0 Sequencing African genomes not only enriches the global genomic dataset but also empowers African scientists and institutions to lead research that directly benefits their communities. This initiative is a significant step toward equitable healthcare, ensuring that the genetic insights derived from African populations<\/span> <span style=\"font-weight: 400;\">contribute to medical advancements and the reduction of health disparities both on the continent and globally.<\/span><\/p><p><b>Any notable partnerships or collaborators<\/b><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Redeemer\u2019s University, Nigeria: Host institution providing foundational support and infrastructure for IGH&#8217;s operations.\u200b<\/span><span style=\"font-weight: 400;\"><br \/><br \/><\/span><\/li><\/ul><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Skoll Foundation: Provided 500k USD in seed funding for the GenCoE Project<\/span><b><br \/><br \/><\/b><\/li><\/ul><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Illumina: Donated NovaSeqX Plus to IGH for human sequencing purposes and pledged support with reagents<\/span><span style=\"font-weight: 400;\"><br \/><br \/><\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Roche: Pledged financial support for reagents and sequencing<\/span><b><br \/><br \/><\/b><\/li><\/ul><p><b>Future goals or vision<\/b><\/p><p><span style=\"font-weight: 400;\">As we look ahead, IGH is focused on fully launching the Human Genome project into full scale. Key upcoming projects for the human genome project include:<\/span><\/p><ul><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Gathering sample provider partners: <\/b><span style=\"font-weight: 400;\">Finding sample providers who can provide sample cohorts for sequencing efforts<\/span><\/li><li style=\"font-weight: 400;\" aria-level=\"1\"><b>Continued African genome sequencing: <\/b><span style=\"font-weight: 400;\">IGH has the ambitious goal of sequencing 3 million African genomes<\/span><\/li><\/ul><p><b>Biobank Expansion<\/b><span style=\"font-weight: 400;\">: Growth and enhancement of our existing Biobank to support a broader range of human genome sequencing efforts<\/span><span style=\"font-weight: 400;\"><br \/><\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>A summary of the Human Genomics Centre The Human Genome Project is a project that was launched in 2024 at the Institute of Genomics and Global Health (IGH), formerly ACEGID, is a groundbreaking project aiming to lead human genomics sequencing in Africa.\u00a0\u00a0 The key focus areas of the work The primary goal of the Human &hellip; <a href=\"https:\/\/ighresearch.org\/en\/human-genomic-centre\/\" class=\"more-link\" title=\"Continue reading <span class=\"screen-reader-text\">Human Genomic Centre<\/span>&#8220;>Continue reading <span class=\"screen-reader-text\">Human Genomic Centre<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"class_list":["post-1629","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/pages\/1629","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/comments?post=1629"}],"version-history":[{"count":4,"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/pages\/1629\/revisions"}],"predecessor-version":[{"id":1634,"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/pages\/1629\/revisions\/1634"}],"wp:attachment":[{"href":"https:\/\/ighresearch.org\/en\/wp-json\/wp\/v2\/media?parent=1629"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}